Discovery and Neurotoxicity
Neurons carrying a GFP-reporter can be used for high-content imaging with automated analysis of neuron morphology such as neurite number, length, and branching complexity.
Motor neurons with a luciferase reporter show a typical S-curve pharmacological response.
Functional Activity - Calcium Influx
Calcium influx of mature neurons (Day 10) can be measured following electric field stimulation.
Functional Activity – Axon Potentials
Axon potential magnitude and frequency can be measured using traditional electrophysiology techniques.
Functional Activity – Multi-Electrode Array (MEA)
Spike activity over the entire culture can be monitored using multi-electrode array.